In this lab we separated components of a simulated preparation, panacetin and making use of its acid base properties. To obtain such a pure compound, the compound we want must be separated from its other natural components, which can be done by manipulating physical and chemical properties. Panacetin contains sucrose, aspirin and an unknown which can be acetanilide or phenacetin in which phenacetin was created and weighed. Introduction
In this lab our basic goal was to make the sucrose, aspirin and unknown that are formed from pharmaceutical panacetin. In doing this lab we used NaOH and diethyl either, along with water. We used a centrifuge to separate the contents with a very thin layer that was later separated which the bottom and top layer forming the sucrose and aspirin and the unknown. We then filtered the solid aspirin that formed after the cooling it in an ice bath and it was then weighed. Chemical Reaction
Wear splash-proof mono goggles at all times.
Wear Chemically resistant Lab Aprons at all times in the lab. No shorts, skirts, sleeveless/half sleeved Shirts and blouses and sandals allowed in lab. No Eating or Drinking in the Lab.
Wear Gloves when handling chemicals
Hydrochloric acid is corrosive. Do not allow it to come in contact with your skin or clothes. Use Caution work and work in Fume Hood.
Ethyl ether extremely flammable, avoid contact with Eyes and skin Toxic if ingested, avoid Inhalation. Use Caution and work in Fume Hood.
All Chemicals are potentially toxic upon ingestion -Use Caution Panacetin prepared in lab is not safe for human consumption
“The procedure for this experiment appears on page 14-17 of the Lab manual.
To help write this lab report I used the organic chemistry lab manual pages 10-17. We used the Microscale section of the procedure during our experiment. We used NaOH and diethyl ether as substitutions for dichloromethane and sodium bicarbonate No chemicals are to go down the drain
In this lab the results were recorded in two sections separated in sucrose and aspirin. The sucrose results were recorded as being in a solid state, having a white color and having a weighed mass of .21 grams. The aspirin results were recorded as a solid state, having a white color and having a weighed a mass of .10 grams. Conclusion
In the end I think my partner and me performed a successful lab, with expected results. We followed through with the procedure and used the substituted chemicals provided by the school. We had three products that were formed which were the sucrose, aspirin and the unknown that was formed with the aspirin.
1. Miller, R.B. Organic Chemistry 205 Lab Manual. Academx Publishing Services: Richmond, VA, 2010. 2. “HOW TO WRITE Organic Reaction Mechanisms, Khalid Ahsan , University at Buffalo